The Shocking New Science Of How To Manage Your Stress - Dr Robert Sapolsky | Modern Wisdom 693

Last updated: Oct 14, 2023

The video is about the science of managing stress and how it affects the human body. The host, Dr. Robert Sapolsky, discusses the impact of stress on the heart, blood pressure, bladder, and brain. He explains that stress can make people less empathetic, less tolerant, and less willing to take another person's perspective. The host also talks about the brain region called the anterior singulate cortex, which is responsible for interpreting pain and is activated when someone else's pain is felt. The video also discusses the role of stress hormones in disrupting the functioning of this brain region and how it affects empathy.

This video by Chris Williamson was published on Oct 14, 2023.
Video length: 01:41:39.

The video is about the science of managing stress and its impact on the human body.

The host, Dr. Robert Sapolsky, discusses how stress can make people less empathetic, less tolerant, and less willing to take another person's perspective. He explains that the worst effect of stress is on the brain, where it can narrow a person's tunnel of concerns and make them less able to understand and empathize with others. Dr. Sapolsky also discusses the role of the anterior singulate cortex in interpreting pain and how it can be affected by stress hormones.

He also talks about how stress can disrupt the functioning of this part of the brain and how it can lead to a decrease in empathy and an increase in self-interest.

  • Stress can make people less empathetic, less tolerant, and less willing to take another person's perspective.
  • Stress can cause crummy things to the heart, blood pressure, bladder, and brain.
  • Stress can make people less generous and more likely to cheat in an economic game.
  • Stress can make people less empathetic and less willing to look at someone else's pain and perspective.
  • Stress can make people less tolerant and less willing to take another person's perspective.
  • The anterior singulate cortex is responsible for interpreting pain and is activated when someone else's pain is felt.
  • The anterior singulate cortex also activates when someone is told they have just had a powerful anesthetic cream smeared over their finger, even though they don't feel the pain.
  • The anterior singulate cortex is overactive in people suffering from major depression, where it is just pain 24/7.
  • Stress hormones disrupt the functioning of the anterior singulate cortex.

The Shocking New Science Of How To Manage Your Stress - Dr Robert Sapolsky | Modern Wisdom 693 - YouTube

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The Impact of Stress on the Human Body

  • Stress can make people less empathetic, less tolerant, and less willing to take another person's perspective.
  • Stress can cause crummy things to the heart, blood pressure, bladder, and brain.
  • Stress can make people less generous and more likely to cheat in an economic game.
  • Stress can make people less empathetic and less willing to look at someone else's pain and perspective.
  • Stress can make people less tolerant and less willing to take another person's perspective.
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The Role of the Anterior Singulate Cortex in Interpreting Pain

  • The anterior singulate cortex is responsible for interpreting pain and is activated when someone else's pain is felt.
  • The anterior singulate cortex also activates when someone is told they have just had a powerful anesthetic cream smeared over their finger, even though they don't feel the pain.
  • The anterior singulate cortex is overactive in people suffering from major depression, where it is just pain 24/7.
  • The anterior singulate cortex is a placebo effect, it's about the interpretation of the pain rather than the nuts and bolts features of it.
  • The anterior singulate cortex is a simplistic level and can't tell the difference between your pain and someone else's pain.
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The Effects of Stress Hormones on the Anterior Singulate Cortex

  • Stress hormones disrupt the functioning of the anterior singulate cortex.
  • Giving a drug to rats or college freshman volunteers that blocks the effects of a stress hormone allows them to maintain their empathy despite being stressed.
  • Stress hormones make people less empathetic and less willing to look at someone else's pain and perspective.
  • Stress hormones make people less tolerant and less willing to take another person's perspective.
  • Stress hormones make people less generous and more likely to cheat in an economic game.
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The Shocking New Science Of How To Manage Your Stress - Dr Robert Sapolsky | Modern Wisdom 693 - YouTube

The Role of Agency and Valuation in Stress

  • Stress can be seen as an agentic view of what's happening to you, it's how much agency do you have.
  • Stress can be seen as an agentic view of what's happening to you, it's how much agency do you have.
  • Stress can be seen as an agentic view of what's happening to you, it's how much agency do you have.
  • Stress can be seen as an agentic view of what's happening to you, it's how much agency do you have.
  • Stress can be seen as an agentic view of what's happening to you, it's how much agency do you have.
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The Science of Managing Stress

  • The host, Dr. Robert Sapolsky, discusses the impact of stress on the heart, blood pressure, bladder, and brain.
  • Stress can make people less empathetic, less tolerant, and less willing to take another person's perspective.
  • The brain region called the anterior singulate cortex is responsible for interpreting pain and is activated when someone else's pain is felt.
  • Stress hormones can disrupt the functioning of this brain region and affect empathy.
  • Short-term stress can be useful, but long-term stress is not.
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The Biology of Stress

  • The central concept in stress is that it can cause a person to get stuck in a traffic jam.
  • The same molecules that are secreted when a person is stressed are also secreted when they are thinking about global warming or other issues.
  • Stress is an ancient piece of art that has been conserved in humans, primates, mammals, fish, birds, and reptiles.
  • Stress helps the body deal with a short-term physical crisis by mobilizing energy from storage sites to the muscles.
  • Chronic stress can lead to corrosive and disastrous psychosocial stress, which can affect a person's cardiovascular system and lead to health problems.
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The Psychology of Stress

  • The idea that a person can get sick from psychological stress is an odd sort of twisting of the words.
  • Humans have an unbelievable abstraction ability to contemplate their stresses and ruminate about them.
  • Even if a person is not being chased by a dinosaur or tiger, they can still get the same physiological effect from imagining previous instances of stress.
  • Chronic stress can lead to corrosive and disastrous psychosocial stress, which can affect a person's cardiovascular system and lead to health problems.
  • The concept of being smart enough to get sick from psychological stress is an odd sort of twisting of the words, but it is true.
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The Impact of Stress on the Heart

  • Stress can cause an increase in heart rate and blood pressure.
  • Chronic stress can lead to heart disease and other cardiovascular problems.
  • Stress can also cause changes in the structure and function of the heart.
  • Stress hormones, such as cortisol and adrenaline, can contribute to these changes.
  • Reducing stress through relaxation techniques and other interventions can help to mitigate the negative effects of stress on the heart.
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The Impact of Stress on Blood Pressure

  • Stress can cause an increase in blood pressure, which can lead to hypertension.
  • Chronic stress can cause long-term changes in blood pressure, increasing the risk of cardiovascular disease.
  • Stress hormones, such as cortisol and adrenaline, can contribute to these changes.
  • Reducing stress through relaxation techniques and other interventions can help to lower blood pressure and reduce the risk of cardiovascular disease.
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The Impact of Stress on the Bladder

  • Stress can cause changes in the bladder's function, including increased urination and decreased bladder control.
  • Chronic stress can lead to bladder problems, such as urinary tract infections and bladder cancer.
  • Stress hormones, such as cortisol and adrenaline, can contribute to these changes.
  • Reducing stress through relaxation techniques and other interventions can help to improve bladder function and reduce the risk of bladder problems.
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The Impact of Stress on the Brain

  • Stress can cause changes in the structure and function of the brain, including changes in brain size and connectivity.
  • Chronic stress can lead to cognitive impairment, including memory loss and difficulty concentrating.
  • Stress hormones, such as cortisol and adrenaline, can contribute to these changes.
  • Reducing stress through relaxation techniques and other interventions can help to improve brain function and reduce the risk of cognitive impairment.
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The Impact of Stress on Empathy

  • Stress can make people less empathetic, less tolerant, and less willing to take another person's perspective.
  • Chronic stress can lead to a decrease in the activity of the anterior cingulate cortex, which is responsible for interpreting pain and is activated when someone else's pain is felt.
  • Stress hormones, such as cortisol and adrenaline, can disrupt the functioning of the anterior cingulate cortex and contribute to a decrease in empathy.
  • Reducing stress through relaxation techniques and other interventions can help to improve empathy and increase the activity of the anterior cingulate cortex.
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The Impact of Stress on the Human Body

  • Stress hormones can have a significant impact on the human body, affecting the heart, blood pressure, bladder, and brain.
  • Chronically high levels of stress hormones can impair the maturation of the frontal cortex, a region of the brain responsible for self-discipline, long-term planning, impulse control, and emotional regulation.
  • Studies have shown that a mother's socioeconomic status and stress levels can predict a child's resting stress hormone levels and the maturation of their frontal cortex by age five.
  • The brain region that lets you be self-disciplined and long-term planning and impulse control and emotional regulation is the frontal cortex.
  • The maturation of the frontal cortex is impaired by chronic stress, which can lead to negative outcomes such as impaired cognitive function and increased risk of mental health disorders.
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The Intersection of Nature and Nurture

  • Behavioral genetics is the study of how genetic factors interact with environmental factors to influence behavior.
  • The predisposition to be anxious in a mother can be inherited by her child, but the environment in which the child grows up can also play a significant role in shaping their behavior.
  • The subtext of the environment in which the child grows up is that the world is a scary place and they need to be vigilant.
  • Behavioral genetics has shown that behavior genes are rarely deterministic and are more about vulnerabilities and potential than specific outcomes.
  • The interplay between genetic potential and environmental factors is crucial in determining behavior and outcomes.
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The Study

  • The study is about the relationship between a specific gene and serotonin, a neurotransmitter in the brain.
  • The gene is associated with an increased risk for depression if a person has experienced a lot of stress during childhood.
  • The study followed thousands of people from childhood to early adulthood, examining their genomes and the impact of stress on depression risk.
  • The study found that the gene variant had no impact on depression risk if a person did not experience significant stress during childhood.
  • The study highlights the importance of considering the environment and stressors when examining the relationship between genes and behavior.
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The Theme

  • The theme of the study is that the genetics of depression are influenced by the environment and stressors experienced during childhood.
  • The study suggests that certain genetic profiles are more vulnerable to depression when coupled with significant stress during childhood.
  • The study highlights the importance of considering the environment and stressors when examining the relationship between genes and behavior.
  • The study suggests that the impact of stress on depression risk can be lifelong and multi-generational.
  • The study emphasizes the importance of understanding the complex interplay between genes, behavior, and the environment in the development of depression.
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The Impact of Stress on Behavior

  • The study suggests that stressors during childhood can have a significant impact on a person's vulnerability to depression.
  • The study highlights the importance of considering the environment and stressors when examining the relationship between genes and behavior.
  • The study suggests that the impact of stress on behavior can be lifelong and multi-generational.
  • The study emphasizes the importance of understanding the complex interplay between genes, behavior, and the environment in the development of depression.
  • The study suggests that the impact of stress on behavior can be influenced by factors such as culture, education, and motivation.
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The Importance of Epigenetics

  • Epigenetics is the study of how experience can change the regulation of genes without changing their DNA sequences.
  • The study suggests that experience can have a significant impact on the regulation of genes, particularly in the context of stress and depression.
  • The study highlights the importance of considering the role of epigenetics in the relationship between genes and behavior.
  • The study suggests that the impact of stress on epigenetics can be lifelong and multi-generational.
  • The study emphasizes the importance of understanding the complex interplay between genes, behavior, and the environment in the development of depression, and the role of epigenetics in this process.
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Epigenetics and Stress

  • Epigenetics is the study of how the environment affects gene regulation.
  • Epigenetic changes can have a lifelong impact on disease risks and diet.
  • Epigenetic effects on the brain can affect pain perception and empathy.
  • Epigenetic changes can be passed down to future generations through parenting style and culture.
  • Multigenerational epigenetic effects can arise from cruel mechanisms, such as maternal stress during fetal life.
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Stress and the Brain

  • Stress can cause epigenetic changes in the amygdala, which is responsible for fear and anxiety.
  • An enlarged amygdala can lead to hyperactivity and hysteria in adults.
  • Elevated levels of stress hormones can also affect the fetus's amygdala, leading to multi-generational effects.
  • Interventions, such as therapy, can reverse epigenetic changes and improve gene regulation.
  • Research on stress reduction strategies can help individuals cope with stress and improve their overall well-being.
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Conclusion

  • Epigenetics and stress have a complex relationship that can affect an individual's health and well-being.
  • Understanding the mechanisms behind epigenetic changes and their impact on the brain can help individuals better manage stress and improve their overall health.
  • Interventions, such as therapy, can help reverse epigenetic changes and improve gene regulation.
  • Research on stress reduction strategies can help individuals cope with stress and improve their overall well-being.
  • It is important to approach stress management with a holistic perspective, considering both the individual's environment and genetics.
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What is Stress?

  • Stress is the psychological response to external unpleasantness.
  • It can make people less empathetic, less tolerant, and less willing to take another person's perspective.
  • Stress can affect the heart, blood pressure, bladder, and brain.
  • It can disrupt the functioning of the brain region called the anterior singulate cortex, which is responsible for interpreting pain and is activated when someone else's pain is felt.
  • Stress hormones can affect the brain region and make it harder to empathize with others.
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The Impact of Stress on the Heart, Blood Pressure, Bladder, and Brain

  • Stress can cause an increase in heart rate and blood pressure.
  • It can lead to bladder problems such as urinary frequency and urgency.
  • Stress can affect the brain and lead to anxiety, depression, and other mental health issues.
  • It can disrupt the functioning of the brain region called the anterior singulate cortex, which is responsible for interpreting pain and is activated when someone else's pain is felt.
  • Stress can make it harder to empathize with others and can lead to social isolation.
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The Role of Stress Hormones in Disrupting the Functioning of the Brain Region

  • Stress hormones such as cortisol and adrenaline can disrupt the functioning of the brain region called the anterior singulate cortex.
  • This can lead to difficulty interpreting pain and can make it harder to empathize with others.
  • Stress hormones can also affect the brain region and make it harder to regulate emotions.
  • This can lead to anxiety, depression, and other mental health issues.
  • Stress hormones can also affect the brain region and make it harder to focus and concentrate.
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The Importance of Social Support in Managing Stress

  • Social support is an important factor in managing stress.
  • It can help buffer against the negative effects of stress on the heart, blood pressure, bladder, and brain.
  • Social support can also help people cope with stress and improve their overall well-being.
  • It can help people feel more connected to others and less isolated.
  • Social support can also help people develop better coping strategies for managing stress.
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The Science of Stress Management

  • Stress can have negative effects on the heart, blood pressure, bladder, and brain.
  • Stress can make people less empathetic, less tolerant, and less willing to take another person's perspective.
  • The brain region called the anterior singulate cortex is responsible for interpreting pain and is activated when someone else's pain is felt.
  • Stress hormones can disrupt the functioning of this brain region and affect empathy.
  • The human brain has a unique reward anticipation system that allows for a wide range of potential pleasures and motivations.
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The Science of Managing Stress

  • Stress can make people less empathetic, less tolerant, and less willing to take another person's perspective.
  • The brain region called the anterior singulate cortex is responsible for interpreting pain and is activated when someone else's pain is felt.
  • Stress hormones can disrupt the functioning of this brain region and affect empathy.
  • The downside of habituating to great things is that they no longer taste as good or feel as satisfying.
  • There are ways to slow the inevitable onslaught of habituation, such as being more mature and paying attention to the viscera of a moment.
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The Role of Dopamine in Habituation

  • Dopamine is a neurotransmitter associated with reward and pleasure.
  • People are concerned about being driven by dopamine and becoming compulsively chasing it through various means.
  • Dopamine Nation is a term used to describe the collective effervescence experience of people with their friends.
  • Dopamine is about reward, and cocaine releases tons of dopamine, leading to addiction.
  • Dopamine is not just about euphoric release, but also about habituation and the ratcheting downward of addiction.
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The Science of Managing Stress

  • The video discusses the impact of stress on the heart, blood pressure, bladder, and brain.
  • Stress can make people less empathetic, less tolerant, and less willing to take another person's perspective.
  • The brain region called the anterior singulate cortex is responsible for interpreting pain and is activated when someone else's pain is felt.
  • Stress hormones can disrupt the functioning of this brain region and affect empathy.
  • Dopamine is released when someone anticipates a reward, not when they receive it.
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The Role of Anticipation in Motivation

  • The anticipation of a reward can be more motivating than the reward itself.
  • Introducing uncertainty in a situation can increase dopamine levels and motivation.
  • Social engineering can be used to convince people to take a chance and press a lever, even if they believe the reward is unlikely.
  • Humans are able to maintain anticipatory dopamine for longer periods of time than animals, which explains an awful lot.
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The Bullseye of Happiness

  • The video suggests that the bullseye of happiness is things are about to get slightly better than expected.
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